Portrait of Dr Laura Waters Dr Laura Waters

l.waters@hud.ac.uk | 01484 472190



Biography

Laura joined the University of Huddersfield in 2003 as a lecturer in pharmaceutical science and is currently a Principal Enterprise Fellow in the School of Applied Sciences. Laura is heavily involved in the RSC, current treasurer of the local section, a Benevolent Volunteer Visitor, a former member of Council and a current member of the JPAG committee. Laura is also part of an APS focus group, a Fellow of the Higher Education Academy, a National Public Engagement Ambassador (NCCPE) and a STEM ambassador.

Laura has an active research group investigating phenomena at the interface of chemistry and pharmaceutics, developing analytical techniques, characterising chemical interactions and enhancing formulations, all funded through external sources. Her work in the area of public engagement includes public lectures and media presentations and she has appeared on BBC1, BBC2, BBC3, Channel 4 and Channel 5.

Research and Scholarship

Development of quantitative structure activity relationships for new chemical entities through the use of calorimetry.

Improvement of chromatographic techniques in pharmaceutical preformulation.

Development of novel pharmaceutical formulations.

Publications and Other Research Outputs

2017

Waters, L (2017) ‘Effect of plasma surface treatment of poly(dimethylsiloxane) on the permeation of pharmaceutical compoundsJournal of Pharmaceutical Analysis . ISSN 2095-1779

Hussain, T., Waters, L., Parkes, G. and Shahzad, Y. (2017) ‘Microwave processed solid dispersions for enhanced dissolution of gemfibrozil using non-ordered mesoporous silicaColloids and Surfaces A: Physicochemical and Engineering Aspects , 520, pp. 428-435. ISSN 0927-7757

Manchester, K., Lomas, E., Waters, L., Dempsey, F. and Maskell, P. (2017) ‘The Emergence of New Psychoactive Substance (NPS) Benzodiazepines: A ReviewDrug Testing and Analysis . ISSN 1942-7603

Bhuiyan, A. and Waters, L. (2017) ‘Permeation of pharmaceutical compounds through silicone membrane in the presence of surfactantsColloids and Surfaces A: Physicochemical and Engineering Aspects , 516, pp. 121-128. ISSN 0927-7757

2016

De Santis, E., Edwards, A., Alexander, B., Holder, S., Biesse-Martin, A., Nielsen, B., Mistry, D., Waters, L., Siligardi, G., Hussain, R., Faure, S. and Taillefumier, C. (2016) ‘Selective complexation of divalent cations by a cyclic ?,?-peptoid hexamer: a spectroscopic and computational study.Organic & Biomolecular Chemistry , 48, pp. 11371-11380. ISSN 1477-0520

Shokry, D., Waters, L., Parkes, G. and Mitchell, J. (2016) ‘The Use of Bile Salt Micelles for the Prediction of Human Intestinal AbsorptionJournal of Pharmaceutical Sciences , 105 (12), pp. 3611-3614. ISSN 0022-3549

Swaine, T., Tang, Y., Garcia, P., John, J., Waters, L. and Lewis, A. (2016) ‘Evaluation of ion exchange processes in drug-eluting embolization beads by use of an improved flow-through elution method.European Journal of Pharmaceutical Sciences , 93, pp. 351-359. ISSN 0928-0987

Ehiwe, T., Alexander, B., Mitchell, J., Snowden, M. and Waters, L. (2016) ‘Monitoring real time polymorphic transformation of sulfanilamide by diffuse reflectance visible spectroscopyJournal of Pharmaceutical Analysis , 6 (3), pp. 179-183. ISSN 2095-1779

Waters, L. and Bhuiyan, A. (2016) ‘Ionisation effects on the permeation of pharmaceutical compounds through silicone membraneColloids and Surfaces B: Biointerfaces , 141, pp. 553-557. ISSN 0927-7765

Waters, L., Shokry, D. and Parkes, G. (2016) ‘Predicting human intestinal absorption in the presence of bile salt with micellar liquid chromatographyBiomedical Chromatography . ISSN 1099-0801

2015

Savage, T., Mitchell, J., Trivedi, V., Wicks, S. and Waters, L. (2015) ‘Continuous Tank Reactor Synthesis of Highly Substituted Sulphobutylether ?-1 CyclodextrinsInternational Journal of Pharmaceutics , 495 (2), pp. 862-868. ISSN 0378-5173

Waters, L., Swaine, T. and Lewis, A. (2015) ‘A calorimetric investigation of doxorubicin-polymer bead interactionsInternational Journal of Pharmaceutics , 493 (1-2), pp. 129-133. ISSN 0378-5173

Waters, L (2015) ‘Recent developments in skin mimic systems to predict transdermal permeationCurrent Pharmaceutical Design , 21 (20), pp. 2725-2732. ISSN 1381-6128

2014

Waters, L., Hussain, T. and Parkes, G. (2014) ‘Thermodynamics of micellisation: Sodium dodecyl sulfate/sodium deoxycholate with polyethylene glycol and model drugsJournal of Chemical Thermodynamics , 77, pp. 77-81. ISSN 0021-9614

Shahzad, Y., Waters, L. and Barber, C. (2014) ‘Solvent selection effects on the transport of compounds through silicone membraneColloids and Surfaces A: Physicochemical and Engineering Aspects , 458, pp. 96-100. ISSN 0927-7757

2013

Waters, L., Shahzad, Y. and Stephenson, J. (2013) ‘Modelling skin permeability with micellar liquid chromatographyEuropean Journal of Pharmaceutical Sciences , 50 (3-4), pp. 335-340. ISSN 0928-0987

Waters, L., Hussain, T., Parkes, G., Hanrahan, J. and Tobin, J. (2013) ‘Inclusion of fenofibrate in a series of mesoporous silicas using microwave irradiationEuropean Journal of Pharmaceutics and Biopharmaceutics , 85 (3 (B)), pp. 936-941. ISSN 0939-6411

Waters, L., Dennis, L., Bibi, A. and Mitchell, J. (2013) ‘Surfactant and temperature effects on paraben transport through silicone membranesColloids and Surfaces B: Biointerfaces , 108, pp. 23-28. ISSN 0927-7765

2012

Waters, L (2012) ‘Titration Calorimetry of Surfactant-Drug Interactions: Micelle Formation and Saturation StudiesJournal of Chemical Thermodynamics , 53, pp. 36-41. ISSN 0021-9614

Waters, L (2012) ‘pH effects in micellar liquid chromatographic analysis for determining partition coefficients for a series of pharmaceutically related compoundsCurrent Pharmaceutical Analysis , 8 (3), pp. 272-277. ISSN 1573-4129

2011

Shahzad, Y. and Waters, L. (2011) ‘Micelle-Water Partition Coeffcients: A potential alternative to octanol-water partition coefficients for pharmaceutical compoundsSwiss Pharma , 33 (10), p. 35. ISSN 0251-1673

Hussain, T., Waters, L. and Parkes, G. (2011) ‘Pharmaceutical Analysis: Drug-micelle interactionsSwiss Pharma , 33 (10), p. 36. ISSN 0251-1673

Waters, L., Bedford, S. and Parkes, G. (2011) ‘Controlled Microwave Processing Applied to the Pharmaceutical Formulation of IbuprofenAAPS PharmSciTech , 12 (4), pp. 1038-1043. ISSN 1530-9932

2010

Waters, L., Bedford, S., Parkes, G. and Mitchell, J. (2010) ‘Influence of lipophilicity on drug–cyclodextrin interactions: A calorimetric studyThermochimica Acta , 511 (1-2), pp. 102-106. ISSN 00406031

Waters, L. and Kasprzyk-Hordern, B. (2010) ‘Micellar chromatographic determination of partition coefficients and associated thermodynamic data for pharmaceutical compoundsJournal of Thermal Analysis and Calorimetry , 102 (1), pp. 343-347. ISSN 1388-6150

Waters, L (2010) ‘Micellar Chromatographic Partition Coefficients - an Alternative to TraditionJournal of Pharmacy and Pharmacology , 62, pp. 1211-1212. ISSN 0022-3573

2009

Bedford, S. and Waters, L. (2009) ‘The application of microwaves to pharmaceutical formulationJournal of Pharmacy and Pharmacology , 61 (S1), p. A54-A55. ISSN 0022-3573

2008

Waters, L., Naz, S. and Hemming, K. (2008) ‘Calorimetric investigations of the hydrolytic degradation for a series of ?-sultamsJournal of Thermal Analysis and Calorimetry , 93 (2), pp. 339-342. ISSN 14182874

2007

Waters, L. and Pavlakis, E. (2007) ‘In vitro controlled drug release from loaded microspheres - dose regulation through formulationJournal of Pharmacy & Pharmaceutical Sciences , 10 (4), pp. 464-472. ISSN 1482-1826

Waters, L., Leharne, S., Mitchell, J. and Hanrahan, J. (2007) ‘Determination of micelle/water partition coefficients and associated thermodynamic data for dialkyl phthalate estersJournal of Thermal Analysis and Calorimetry , 90 (1), pp. 283-288. ISSN 1388-6150

2005

Waters, L., Leharne, S. and Mitchell, J. (2005) ‘Saturation determination of micellar systems using isothermal titration calorimetryJournal of Thermal Analysis and Calorimetry , 80 (1), pp. 43-47. ISSN 1388-6150

2001

Beezer, A., Hills, A., O�Neill, M., Morris, A., Kierstan, K., Deal, R., Waters, L., Hadgraft, J., Mitchell, J., Connor, J., Orchard, J., Willson, R., Hofelich, T., Beaudin, J., Wolf, G., Baitalow, F., Gaisford, S., Lane, R., Buckton, G., Phipps, M., Winneke, R., Schmitt, E., Hansen, L., O�Sullivan, D. and Parmar, M. (2001) ‘The imidazole catalysed hydrolysis of triacetin: an inter- and intra-laboratory development of a test reaction for isothermal heat conduction microcalorimeters used for determination of both thermodynamic and kinetic parametersThermochimica Acta , 380 (1), pp. 13-17. ISSN 0040-6031

Research Degree Supervision

My research focuses on pharmaceutics and physical chemistry, incorporating preformulation and formulation aspects of pharmaceutical interest. If you are interested in working with Dr Waters please e-mail your CV with a covering letter to l.waters@hud.ac.uk.

Enterprise Activities

Science Communication/Outreach Activities